Probiotic Biotherapy for Eradication of a Potential Pathogen in a Commercial Rat Breeding Facility

  • Eje Collinder Depatment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm and Mälaren Horse Hospital, Sigtuna
  • Johannes Bergstedt Depatment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm
  • Anna-Karin Persson Depatment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm
  • Elisabeth Norin Depatment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm
  • Tore Midtvedt Depatment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm

Abstract

This study defined a model for biotherapeutic eradication of beta-haemolytic streptococci, group G, in a rat  breeding unit (3100 rats) by use of a strain of Lactobacillus reuteri. The microbe was added to the rats’  drinking water and the genitals of all rats were swabbed three times with a solution of the microbe. After this  procedure undesirable streptococci were not recognized in any animal of this breeding farm. 

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