#6 Stability of Clinical Chemistry and Hematological Analytes in Preserved Plasma and Blood Obtained from Wistar Rats

  • M Singh Drug Safety Assessment, Novel Drug Discovery & Development, Lupin Limited (Research Park), Pune
  • R Pandya Drug Safety Assessment, Novel Drug Discovery & Development, Lupin Limited (Research Park), Pune
  • S Chandra Drug Safety Assessment, Novel Drug Discovery & Development, Lupin Limited (Research Park), Pune
  • S K Sharma Drug Safety Assessment, Novel Drug Discovery & Development, Lupin Limited (Research Park), Pune

Abstract

Blood samples obtained from experimental animals often need preservation due to several technical constraints. The present study was aimed to determine the effect of storage temperature and time on the stability of analytes in whole blood and plasma samples obtained from Wistar rats. Aspartate amino transferase, alkaline phosphatase, cholesterol, triglycerides, creatinine, urea, glucose, total protein, total bilirubin, phosphorous, sodium, potassium and chloride did not show statistically significant changes in plasma preserved at
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